22 Sep 1941
- German submarine U-562 sank British ship Erna III 200 miles east of Iceland at 0233 hours, killing all 25 aboard. ww2dbase [CPC]
- German submarines U-68 attacked Allied convoy SL-87 300 miles west of the Canary Islands at 0222 hours, damaging British merchant ship Silverbelle. At 2346 hours, U-103 attacked the same convoy, sinking British merchant ships Edward (all 63 aboard survived) and Niceto de Larrinaga Blyden (2 killed, 53 survived). ww2dbase [CPC]
- British minelaying cruiser HMS Abdiel and destroyers HMS Kandahar, HMS Jaguar, and HMS Griffin departed Alexandria, Egypt with supplies for Tobruk, Libya. They would arrive overnight and return on the following day. ww2dbase [Siege of Tobruk | CPC]
- The Jager Report (issued on 1 Dec 1941) noted that 512 adult male, 744 adult female, and 511 children, all Jews, were killed in Riess, Lithuania for a total of 1,767 people. ww2dbase [Discovery of Concentration Camps and the Holocaust | CPC]
- The US 1st Marine Brigade (Provisional) was placed under the command of the US Army's Iceland Base Command. ww2dbase [AC]
- Friedrich-Wilhelm Müller was awarded the Knight's Cross of the Iron Cross. ww2dbase [Friedrich-Wilhelm Müller | CPC]
- German Stuka dive bombers damaged Soviet destroyer Bezuprechny at 1300 hours, destroyer Besposhchadny at 1630 hours, and destroyer Boyki in the Black Sea off Odessa, Ukraine. ww2dbase [Siege of Odessa | CPC]
- Comandante Cappellini arrived at Bordeaux, France at 1315 hours, ending her seventh war patrol. ww2dbase [Comandante Cappellini | Bordeaux, Aquitaine | CPC]
- Seaplane tender Hans Albrecht Wedel was completed at the F. Schichau yard in Königsburg, Germany. ww2dbase [F. Schichau Königsburg | Hans Albrecht Wedel | Königsburg, Ostpreußen | CPC]
- British cruiser HMS London departed Scapa Flow, Scotland, United Kingdom with Lord Beaverbrook and Averell Harriman aboard for Archangel, Russia for Lend-Lease discussions. She was escorted by Soviet and British destroyers. ww2dbase [Scapa Flow | London | Scapa Flow, Scotland | CPC]
- King George II of the Hellenes, with members of his family and government who have escaped from Crete, Greece arrived in England, United Kingdom. ww2dbase [George II | England | AC]

22 Sep 1941 Interactive Map
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